Though variations in the arterial pattern of upper limb are fairly common, a bilateral presentation as encountered in this case, i.e. superficial brachial artery seen bilaterally in an adult female cadaver is extremely rare. Its origin, course and termination were different in both the limbs. On the left side, the brachial artery in the middle 1/3rd of arm, coursed superficial to the median nerve and on the right side it divided in upper 1/3rd of arm into superficial and deep arteries. Former coursed superficial to median nerve and terminated in the cubital fossa by dividing into radial and ulnar artery while the latter coursed deep to median nerve and continued as common interosseous artery. Superficial brachial artery is reported earlier by different authors in frequency range of 0.2–25%, but mostly unilaterally. Further ontogeny and clinical implications of the variant are explained in detail.