The complex embryologic development of the vascular system often results in a myriad of clinically relevant variants. The classic anatomic venous pattern in the lower extremity is found in only 16 percent of subjects with 2% occurrence of duplication of superficial femoral vein. A good clinical review of retrospective and prospective studies with various investigation modalities reveals an unprecedented relation between duplicated femoral veins and deep vein thrombosis. So the basic purpose or aim of reporting the case of duplication of femoral vein was to highlight the misnomer attached to the femoral vein and to emphasize through clinical review that more cases of proximal thrombosis have false-negative findings with duplication than with single femoral vein. Also, an attempt has been made to elaborate its embryological and clinical aspects in detail.