ABSTRACT: Endoscopic submucosal dissection (ESD) is a new safe and effective technique of endoscopic technique with minimally invasive. This technique makes the en-bloc resection of larger lesions finished more safely and effectively, and provides complete specimen for pathological diagnosis so as to prevent recurrence. It is the first choice for the management of premalignant lesions and early gastric cancer. The elevated risk of compications and technical complexity of endoscopic submuscosal dissection has limited its implementation in our medical system. With propels in endoscopic hardware and strategies, endoscopic mucosal resection (EMR) and endoscopic submucosal dismemberment (ESD) have become built up medicines for the protected and compelling expulsion of mucosal sores of the throat, stomach, duodenum and colon. The compelling resection of these sores takes into account the endoscopic fix and additionally complete organizing of gastrointestinal, mucosal, neoplastic injuries in these individual organs. EMR and ESD are currently routinely performed at numerous huge volume referral clinical focuses, for example, Penn State Health Milton S. Hershey Medical Center and have changed the administration of these injuries all through the gastrointestinal tract by permitting powerful resection without the requirement for significant medical procedure. Signs for EMR and ESD include: Mucosal injuries of the throat (harmful or possibly malignant) including knobs or masses inside Barrett's Esophagus and short portion Barrett's Esophagus with dysplasia.
