To report two brothers who have Usher's syndrome. Two brothers, 24 and 26, reported to the Chittagong eye hospital and training complex with symptoms of progressive vision loss in both eyes, particularly at night. Their greatest corrected visual acuity was 6/36 in the right eye and 6/24 in the left eye, according to their ocular exams. Pigmentary retinopathy was discovered during a dilated fundus examination. Perimetry exhibited a narrowing of the peripheral visual field Sensorineural hearing loss was discovered during their systematic assessment. These are clinical trials. The Usher syndrome Type 1 was diagnosed based on the findings. Low vision aids were recommended to the patients in order to enhance their eyesight. The patient's family members were assessed for quality of life and counseled about the disease's prognosis. Early identification and treatment will assist to maintain the remaining eyesight. the patients in order to enhance their eyesight. The patient's family members were assessed for quality of life and counseled about the disease's prognosis. Early identification and treatment will assist to maintain the remaining eyesight.